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Nov 05
1

Programma Sei Artisti per la Ricerca

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May 17
0

Pubblicazioni Scientifiche Negli Ultimi 10 Anni

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  1. Familial Alzheimer’s disease sustained by presenilin 2 mutations: Systematic review of literature and genotype-phenotype correlation.

    Canevelli M, Piscopo P, Talarico G, Vanacore N, Blasimme A, Crestini A, Tosto G, Troili F, Lenzi GL, Confaloni A, Bruno G.
    Neurosci Biobehav Rev. 2014

  2. Thapsigargin affects presenilin-2 but not presenilin-1 regulation in SK-N-BE cells.

    Rivabene R, Visentin S, Piscopo P, Nuccio CD, Crestini A, Svetoni F, Rosa P, Confaloni A.
    Exp Biol Med. 2014; 239 (2):213-24.

  3. Autosomal dominant frontotemporal lobar degeneration due to the C9ORF72 hexanucleotide repeat expansion: late-onset psychotic clinical presentation.

    Galimberti D, Fenoglio C, Serpente M, Villa C, Bonsi R, Arighi A, Fumagalli GG, Del Bo R, Bruni AC, Anfossi M, Clodomiro A, Cupidi C, Nacmias B, Sorbi S, Piaceri I, Bagnoli S, Bessi V, Marcone A, Cerami C, Cappa SF, Filippi M, Agosta F, Magnani G, Comi G, Franceschi M, Rainero I, Giordana MT, Rubino E, Ferrero P, Rogaeva E, Xi Z, Confaloni A, Piscopo P, Bruno G, Talarico G, Cagnin A, Clerici F, Dell’Osso B, Comi GP, Altamura AC, Mariani C, Scarpini E.
    Biol Psychiatry. 2013;74 (5) :384-91.

  4. Gender differences in Parkinson’s disease: focus on plasma α-synuclein.

    Caranci G, Piscopo P, Rivabene R, Traficante A, Riozzi B, Castellano AE, Ruggieri S, Vanacore N, Confaloni A.
    J Neural Transm. 2013;120 (8): 1209-15.

  5. Pharmacogenomics in Alzheimer’s disease: a genome-wide association study of response to cholinesterase inhibitors.

    Martinelli-Boneschi F, Giacalone G, Magnani G, Biella G, Coppi E, Santangelo R, Brambilla P, Esposito F, Lupoli S, Clerici F, Benussi L, Ghidoni R, Galimberti D, Squitti R, Confaloni A, Bruno G, Pichler S, Mayhaus M, Riemenschneider M, Mariani C, Comi G, Scarpini E, Binetti G, Forloni G, Franceschi M, Albani D.
    Neurobiol Aging.2013; 34 (6):1711.e7-13.

  6. Gender effects on plasma PGRN levels in patients with Alzheimer’s disease: a preliminary study.

    Piscopo P, Rivabene R, Galimberti D, Crestini A, Talarico G, Vanacore N, Scarpini E, Bruno G, Confaloni A.
    J Alzheimers Dis. 2013; 35 (2): 313-8.

  7. Sex effect on presenilins expression in post-natal rat brain.

    Paola Piscopo, Sonia Canterini, Valentina Carletti, Paolo Rosa, Alessio Crestini, Maria Teresa Fiorenza, Annamaria Confaloni
    Advances in Bioscience and Biotechnology, 2013,4,1086-1094.

  8. Increased levels of acute-phase inflammatory proteins in plasma of patients with sporadic CJD.

    Fratini F, Principe S, Puopolo M, Ladogana A, Poleggi A, Piscopo P, Bruno G, Castrechini S, Pascone R, Confaloni A, Minghetti L, Cardone F, Pocchiari M, Crescenzi M.
    Neurology. 2012;79 (10):1012-8.

  9. Replication Study to Confirm the Role of CYP2D6 Polymorphism rs1080985 on Donepezil Efficacy in Alzheimer’s Disease Patients.

    Albani D, Boneschi FM, Biella G, Giacalone G, Lupoli S, Clerici F, Benussi L, Ghidoni R, Galimberti D, Squitti R, Mariani S, Confaloni A, Bruno G, Mariani C, Scarpini E, Binetti G, Magnani G, Franceschi M, Forloni G.
    J Alzheimers Dis. 2012;30 (4) :745-9..

  10. Presenilin 2 mutation R71W in an Italian early-onset sporadic Alzheimer’s disease case.

    Piscopo P, Talarico G, Malvezzi-Campeggi L, Crestini A, Rivabene R, Gasparini M, Tosto G, Vanacore N, Lenzi GL, Bruno G, Confaloni A.
    J Neurol. 2011;258 (11): 2043-7.

  11. Altered oxidative stress profile in the cortex of mice fed an enriched branched-chain amino acids diet:possible link with amyotrophic lateral sclerosis?

    Piscopo P, Crestini A, Adduci A, Ferrante A, Massari M, Popoli P, Vanacore N, Confaloni A.
    J Neurosci Res. 2011; 89 (8):1276-83.

  12. Rosuvastatin and thapsigargin modulate γ-secretase gene expression and APP processing in a human neuroglioma model.

    Crestini A, Piscopo P, Iazeolla M, Albani D, Rivabene R, Forloni G, Confaloni A.
    J Mol Neurosci. 2011;43 (3):461-9.

  13. Hypoxia induces up-regulation of progranulin in neuroblastoma cell lines.

    Piscopo P, Rivabene R, Adduci A, Mallozzi C, Malvezzi-Campeggi L, Crestini A, Confaloni A.
    Neurochem Int. 2010; 57 (8): 893-8.

  14. The London APP mutation (Val717Ile) associated with early shifting abilities and behavioral changes in two Italian families with early-onset Alzheimer’s disease.

    Talarico G, Piscopo P, Gasparini M, Salati E, Pignatelli M, Pietracupa S, Malvezzi-Campeggi L, Crestini A, Boschi S, Lenzi GL, Confaloni A, Bruno G.
    Dement Geriatr Cogn Disord. 2010;29 (6):484-90.

  15. A novel mutation in the predicted TM3 domain of the PSEN2 gene in an Italian pedigree with atypical Alzheimer’s disease.

    P. Piscopo, G. Talarico, A. Crestini, M. Gasparini, L. Malvezzi-Campeggi, E. Piacentini, G. L. Lenzi, G. Bruno and A. Confaloni.
    J Alzheimers Dis. 2010;20 (1):43-7.

  16. Gene Expression Profiles of APP and BACE1 in Tg SOD1G93A Cortical Cells.

    O. Spadoni, A. Crestini, P. Piscopo, L. Malvezzi-Campeggi, I. Carunchio, M. Pieri, C. Zona, A. Confaloni.
    Cell Mol Neurobiol (2009) 29:635–641

  17. A Novel PSEN2 mutation associated with a peculiar phenotype.

    P. Piscopo, G. Marcon, M.R. Piras, A Crestini, L. Malvezzi Campeggi, E. Deiana, R. Cherchi, F. Tanda, A. Deplano, N. Vanacore, F. Tagliavini, M. Pocchiari, G. Giaccone and A. Confaloni.
    Neurology (2008);70 (17):1549-54.

  18. Altered expression of cyclooxygenase-2, presenilins and oxygen radical scavenging enzymes in a rat model of global perinatal asphyxia.

    Piscopo P, Bernardo A, Calamandrei G, Venerosi A, Valanzano A, Bianchi D, Confaloni A, Minghetti L.
    Exp Neurol. (2008);209 (1):192-8;

  19. gamma-Secretase is differentially modulated by alterations of homocysteine cycle in neuroblastoma and glioblastoma cells.

    Fuso A, Cavallaro RA, Zampelli A, D’Anselmi F, Piscopo P, Confaloni A, Scarpa S.
    J Alzheimers Dis. (2007);11(3):275-90.

  20. Presenilin-1 mutation E318G and familial Alzheimer’s disease in the Italian population.

    Albani D, Roiter I, Artuso V, Batelli S, Prato F, Pesaresi M, Galimberti D, Scarpini E, Bruni A, Franceschi M, Piras MR, Confaloni A, Forloni G.
    Neurobiol Aging. (2007);28 (11):1682-8.

  21. Changes in cholesterol metabolism are associated with Presenilin 1 and Presenilin 2 gene regulation in SK-N-BE.

    Crestini A, Napolitano M, Piscopo P, Confaloni A, Bravo E.
    J Mol Neurosci. (2006);30 (3):311-22.

  22. Cognitive deficits in familial Alzheimer’s disease associated with M239V mutation of presenilin 2.

    Giovagnoli AR, Marcon G, Giaccone G, Confaloni A, Tagliavini F.
    Dement Geriatr Cogn Disord. (2006);22 (3):238-43.

  23. Genetic study of Sardinian patients with Alzheimer’s disease.

    Piscopo P, Manfredi A, Malvezzi-Campeggi L, Crestini A, Spadoni O, Cherchi R, Deiana E, Piras MR, Confaloni A.
    Neurosci Lett. (2006); 398 (1-2):124-8.

  24. PEN-2 gene mutation in a familial Alzheimer’s disease case.

    Sala Frigerio C, Piscopo P, Calabrese E, Crestini A, Malvezzi Campeggi L, Civita di Fava R, Fogliarino S, Albani D, Marcon G, Cherchi R, Piras R, Forloni G, Confaloni A.
    J Neurol.(2005); 252 (9):1033-6.

  25. Rat nicastrin gene: cDNA isolation, mRNA variants and expression pattern analysis.

    Confaloni A, Crestini A, Albani D, Piscopo P, Malvezzi Campeggi L, Terreni L, Tartaglia M, Forloni G.
    Brain Res Mol Brain Res. (2005);136 (1-2): 12-22.

May 03
0

ASANT Cafe benefits Alzheimer sufferers

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People with dementia and their caregivers have a new online resource with the launch of the ASANT CafŽ Wednesday. “The ASANT Cafe is an online gathering place. It’s particularly relevant to people living in rural areas who can then go online and have a place to discuss issues around Alzheimer’s disease and related dementias,” said Brenda Hill, manager of client services and programs for the Lethbridge branch of the Alzheimer Society of Alberta and Northwest Territories. The Alzheimer Society has a training program called Seeds of Hope and all training sessions are on the website. The training is suitable for professionals and caregivers. “It reinforces the training around Alzheimer’s disease person-centred care,” Hill said. The ASANT CafŽ also provides information on the disease and its progression and contact information. The society’s First Link program allows people to connect to support, get referrals to health-care providers and community services, meet others in similar circumstances, and get help to plan for the future. “It’s all part of connecting people with Alzheimer’s disease and their families and caregivers to accurate information and to other people who are going through the disease process and requiring assistance on many levels,” Hill said. “We do referrals to many of the care providers in our region.”
The website also offers discussion boards and a place to ask questions so people can find support in a virtual community. “Support is a big part of the site and we certainly notice here in southern Alberta where people are isolated in smaller areas,” she said. ASANT Cafè is funded by Alberta Health and is designed to provide a resource for anyone who’s life is touched by dementia, regardless of where they live in Alberta. The website offers the best that technology currently offers.